DONGMIN's LAB
Optogenetics and Synthetic biology for Neuroscience

* Co-first, ** Co-corresponding authors

2023

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Mingguang Cui, Seunghwan Lee, Sung Hwan Ban, Jae Ryun Ryu, Meiying Shen, Soo Hyun Yang, Jin Young Kim, Seul Ki Choi, Jaemin Han, Yoonhee Kim, Kihoon Han, Donghun Lee, Woong Sun, Hyung-Bae Kwon, Dongmin Lee.

A single-component, light-assisted uncaging switch for endoproteolytic release. Nature Chemical Biology, in press, 2023

 

Soo Hyun Yang*, Esther Yang*, Jaekwang Lee*, Jin Yong Kim*, Hyeijung Yoo, Hyung Sun Park, Jin Taek Jung, Dongmin Lee, Sungkun Chun, Yong Sang Jo, Gyeong Hee Pyeon, Jae-Yong Park, Hyun Woo Lee**, Hyun Kim**.

Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice, Nature Communications, 14 (1), 2435, 2023

 

Seunghwan Lee, Mingguang Cui, Donghun Lee, Kihoon Han, Woong Sun, Dongmin Lee.

A rationally designed optochemogenetic switch for activating canonical Wnt signaling. iScience 26 (3), 106233, 2023

 

Jungbae Yoon, Jun Hwan Moon, Jugyeong Chung, Yu Jin Kim, Kihwan Kim, Hee Seong Kang, Yoo Sang Jeon, Eunsoo Oh, Sun Hwa Lee, Kihoon Han, Dongmin Lee, Chul‐Ho Lee, Young Keun Kim**, Donghun Lee**.

Exploring the Magnetic Properties of Individual Barcode Nanowires using Wide‐Field Diamond Microscopy. Small, 2304129, 2, 2023

 

Muwon Kang*, Yinhua Zhang*, Hyae Rim Kang*, Seoyeong Kim, Ruiying Ma, Yunho Yi, Seungjoon Lee, Yoonhee Kim, Huiling Li, Chunmei Jin, Dongmin Lee, Eunjoon Kim**, Kihoon Han**.

CYFIP2 p.Arg87Cys Causes Neurological Defects and Degradation of CYFIP2. Annals of Neurology, 93 (1), 155-163, 4, 2023

 

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2022

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Jung Ho Hyun*, Kenichiro Nagahama*, Ho Namkung*, Neymi Mignocchi, Seung-Eon Roh, Patrick Hannan, Sarah Krüssel, Chuljung Kwak, Abigail McElroy, Bian Liu, Mingguang Cui, Seunghwan Lee, Dongmin Lee, Richard L Huganir, Paul F Worley, Akira Sawa, Hyung-Bae Kwon.

Tagging active neurons by soma-targeted Cal-Light. Nature communications, 13 (1), 7692, 5, 2022

 

Dongmin Lee, Hyung-Bae Kwon.

Current and future techniques for detecting oxytocin: Focusing on genetically-encoded GPCR sensors. Journal of Neuroscience Methods, 366, 109407, 6, 2022

 

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2019

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Seo Jung Mo, Yongsang Cho, Byung-il Choi, Dongmin Lee**, Hyun Kim**.

PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3. Biochemical and biophysical research communications, 508 (1), 52-59, 2, 2019

 

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2017

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Dongmin Lee*, Jung Ho Hyun*, Kanghoon Jung, Patrick Hannan, Hyung-Bae Kwon.

A calcium-and light-gated switch to induce gene expression in activated neurons. Nature biotechnology, 35 (9), 858-863, 126, 2017

 

Dongmin Lee*, Meaghan Creed*, Kanghoon Jung*, Thomas Stefanelli, Daniel J Wendler, Won Chan Oh, Neymi Layne Mignocchi, Christian Lüscher, Hyung-Bae Kwon.

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Nature methods, 14 (5), 495-503, 123, 2017

 

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2016

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Eunkyung Lie, Ji Seung Ko, Su-Yeon Choi, Junyeop Daniel Roh, Yi Sul Cho, Ran Noh, Doyoun Kim, Yan Li, Hyeyeon Kang, Tae-Yong Choi, Jungyong Nam, Won Mah, Dongmin Lee, Seong-Gyu Lee, Ho Min Kim, Hyun Kim, Se-Young Choi, Ji Won Um, Myoung-Goo Kang, Yong Chul Bae, Jaewon Ko, Eunjoon Kim.

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion. Nature communications, 7 (1), 12328, 31, 2016

 

Sooyoung Chung*, Il Hwan Kim*, Dongmin Lee*, Kyungjoon Park, Joo Yeon Kim, Yeon Kyung Lee, Eun Joo Kim, Hyun Woo Lee, June-seek Choi, Gi Hoon Son, Woong Sun, Ki Soon Shin, Hyun Kim.

The role of inositol 1, 4, 5-trisphosphate 3-kinase A in regulating emotional behavior and amygdala function. Scientific reports, 6 (1), 23757, 12, 2016

 

Ji Won Um*, Tae-Yong Choi*, Hyeyeon Kang, Yi Sul Cho, Gayoung Choii, Pavel Uvarov, Dongseok Park, Daun Jeong, Sangmin Jeon, Dongmin Lee, Hyun Kim, Seung-Hee Lee, Yong-Chul Bae, Se-Young Choi, Matti S Airaksinen, Jaewon Ko.

LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding. Cell reports, 14 (4), 808-822,  68, 2016

 

Seil Jang*, Daeyoung Oh*, Yeunkum Lee*, Eric Hosy*, Hyewon Shin, Christoph Van Riesen, Daniel Whitcomb, Julia M Warburton, Jihoon Jo, Doyoun Kim, Sun Gyun Kim, Seung Min Um, Seok-kyu Kwon, Myoung-Hwan Kim, Junyeop Daniel Roh, Jooyeon Woo, Heejung Jun, Dongmin Lee, Won Mah, Hyun Kim, Bong-Kiun Kaang, Kwangwook Cho, Jeong-Seop Rhee**, Daniel Choquet**, Eunjoon Kim**.

Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nature neuroscience, 19 (1), 84-93, 47, 2016

 

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2015

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Hanwool Park, Jinhee Yang, Ryunhee Kim, Yan Li, Yeunkum Lee, Chungwoo Lee, Jongil Park, Dongmin Lee, Hyun Kim, Eunjoon Kim.

Mice lacking the PSD-95–interacting E3 ligase, Dorfin/Rnf19a, display reduced adult neurogenesis, enhanced long-term potentiation and impaired contextual fear conditioning. Scientific reports, 5 (1), 16410, 28, 2015

 

Jiwon Mo, Chong‐Hyun Kim, Dongmin Lee, Woong Sun, Hyun Woo Lee**, Hyun Kim**.

Early growth response 1 (Egr‐1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus. Journal of neurochemistry, 133 (4), 489-500, 33, 2015

 

Jiseok Lee, Changuk Chung, Seungmin Ha, Dongmin Lee, Do-Young Kim, Hyun Kim, Eunjoon Kim.

Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit. Frontiers in cellular neuroscience, 9, 94,163, 2015

 

Ji Seung Ko, Gopal Pramanik, Ji Won Um, Ji Seon Shim, Dongmin Lee, Kee Hun Kim, Gug-Young Chung, Giuseppe Condomitti, Ho Min Kim, Hyun Kim, Joris de Wit, Kang-Sik Park, Katsuhiko Tabuchi, Jaewon Ko.

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission. Proceedings of the National Academy of Sciences, 112 (6), 1874-1879, 99, 2015

 

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2014

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Dongmin Lee, Seungrie Han, Seungkyun Woo, Hyun Woo Lee, Woong Sun, Hyun Kim.

Enhanced expression and purification of inositol 1, 4, 5-trisphosphate 3-kinase A through use of the pCold1-GST vector and a C-terminal hexahistidine tag in Escherichia coli. Protein Expression and Purification, 97, 72-80, 5, 2014

 

Ji Won Um, Gopal Pramanik, Ji Seung Ko, Min-Young Song, Dongmin Lee, Hyun Kim, Kang-Sik Park, Thomas C Südhof, Katsuhiko Tabuchi, Jaewon Ko.

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Cell reports, 6 (6), 1096-1109, 84, 2014

 

Seungrie Han, Soontaek Hong, Jiwon Mo, Dongmin Lee, Eunju Choi, June-seek Choi, Woong Sun, Hyun Woo Lee**, Hyun Kim**.

Impaired extinction of learned contextual fear memory in early growth response 1 knockout mice. Molecules and cells, 37 (1), 24, 13, 2014

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2013

 

Jooyeon Woo*, Seok-Kyu Kwon*, Jungyong Nam*, Seungwon Choi*, Hideto Takahashi*, Dilja Krueger, Joohyun Park, Yeunkum Lee, Jin Young Bae, Dongmin Lee, Jaewon Ko, Hyun Kim, Myoung-Hwan Kim, Yong Chul Bae, Sunghoe Chang, Ann Marie Craig**, Eunjoon Kim**.

The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development. Journal of Cell Biology, 201 (6), 929-944, 94, 2013

 

Kangduk Lee*, Yoonji Kim*, Sung-Jin Lee, Yuan Qiang, Dongmin Lee, Hyun Woo Lee, Hyun Kim, H Shawn Je, Thomas C Südhof, Jaewon Ko.

MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development. Proceedings of the National Academy of Sciences, 110 (1), 336-341, 127, 2013

 

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2012

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H Yeo, H-w Kim, J Mo, D Lee, S Han, S Hong, MJ Koh, W Sun, S Choi, IJ Rhyu, H Kim**, HW Lee**.

Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus. Neuroscience, 225, 35-43, 11, 2012

 

Seungrie Han, Soontaek Hong, Dongmin Lee, Myeong-hoe Lee, June-seek Choi, Min Jung Koh, Woong Sun, Hyun Kim**, Hyun Woo Lee**.

Altered expression of synaptotagmin 13 mRNA in adult mouse brain after contextual fear conditioning. Biochemical and biophysical research communications, 425 (4), 880-885, 19, 2012

 

Jiwon Mo, Dongmin Lee, Soontaek Hong, Seungrie Han, Hyojin Yeo, Woong Sun, Sukwoo Choi, Hyun Kim**, Hyun Woo Lee**.

Preso regulation of dendritic outgrowth through PI(4,5)P2‐dependent PDZ interaction with βPix. European Journal of Neuroscience, 36 (1), 1960-1970, 14, 2012

 

Eui Ho Hwang, Poong Gi Ahn, Dong Min Lee, Hyeok Su Kim.

Cerebral toxoplasmosis combined with disseminated tuberculosis. Journal of Korean Neurosurgical Society, 51 (5), 316-319, 17, 2012

 

Dongmin Lee, Hyun Woo Lee, Soontaek Hong, Byung-Il Choi, Hyun-wook Kim, Seung Baek Han, Il Hwan Kim, Jin Young Bae, Yong Chul Bae, Woong Sun, Hyun Kim.

Inositol 1, 4, 5-Trisphosphate 3-Kinase A Is a Novel Microtubule-associated Protein. Journal of Biological Chemistry, 287 (19), 15981-15995, 11, 2012

 

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2009

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Seung Baek Han, Byung-il Choi, Dongmin Lee, Sun-Ho Kee, Hyeon Soo Kim, Woong Sun, Hyun Kim.

Regulation of AHI1 expression in adult rat brain: Implication in hypothalamic feeding control. Biochemical and biophysical research communications, 390 (3), 535-540, 2009